Revelation 22:2 PART I: The Voyage of Life

“In the midst of the street of it, and on either side of the river, was there the tree of life, which bare twelve manner of fruits, and yielded her fruit every month: and the leaves of the tree were for the healing of the nations.” Revelation 22:2

Thomas Cole painted “The Voyage of Life” in 1842. The paintings represent the stages of human life: childhood, youth, manhood, and old age. The paintings follow a voyager who travels in a boat on a river, the river of life.

The landscape, corresponding to the seasons of the year, plays a major role in telling the story.

In childhood, the infant glides from a dark cave into a rich, green landscape.

As a youth, the boy takes control of the boat and aims for a shining castle in the sky.

In manhood, the adult relies on prayer and religious faith to sustain him through rough waters and a threatening landscape.

Finally, the man becomes old and the angel guides him to heaven across the waters of eternity.


Aside from the obvious...What do you suppose this RIVER is? Tree of life? Twelve manner of fruits?

Would there be references to these in the Genes/DNA?

In part I of this series let’s talk about this RIVER.

The River STYX

In Greek mythology, is a deity and a river that forms the boundary between Earth and the Underworld.

According to some versions, the river Styx had miraculous powers which could make someone who bathed in the waters invulnerable.

According to one tradition, Achilles' mother dipped him in the river during his childhood and he thus acquired invulnerability, with the exception of the heel by which his mother held him. Achilles was struck and killed during the Trojan War by an arrow shot into his heel by Paris. This is the source of the expression "Achilles' heel", a metaphor for a vulnerable spot.

If you remember correctly Jesus himself descended down after his crucifixion.

In the Hebrew Scriptures, the word used to describe the realm of the dead is sheol. It simply means “the place of the dead” or “the place of departed souls/spirits.” The New Testament Greek equivalent of sheol is hades, which also refers to “the place of the dead.” Other Scriptures in the New Testament indicate that sheol/hades is a temporary place, where souls are kept as they await the final resurrection and judgment.

Now…I’m not here to debate religion. However, the ancient writings are CLEAR!

Sheol/hades was a realm with two divisions—a place of blessing and a place of judgment (Matthew 11:23; 16:18; Luke 10:15; 16:23; Acts 2:27–31). The abodes of the saved and the lost are both generally called “hades” in the Bible. The abode of the saved is also called “Abraham’s bosom” (KJV) or “Abraham’s side” (NIV) in Luke 16:22 and “paradise” in Luke 23:43.

The abode of the unsaved is called “hell” (KJV) or “Hades” (NIV) in Luke 16:23. The abodes of the saved and the lost are separated by a “great chasm” (Luke 16:26).

When Jesus died, He went to the blessed side of sheol and, from there, took the believers with Him to heaven (Ephesians 4:8–10). The judgment side of sheol/hades has remained unchanged. All unbelieving dead go there awaiting their final judgment in the future. Did Jesus go to sheol/hades? Yes, according to Ephesians 4:8–10 and 1 Peter 3:18–20.

So Jesus himself took a ride on the STYX RIVER DOWNWARD!

The STYX Gene

STYX (Serine/Threonine/Tyrosine Interacting Protein) acts as a nuclear anchor for MAPK1.

MAPK1 is related to THE TREE OF LIFE GENE (GRB2/Protein ASH) through the cross talk of a gene called GAREM (GRB2 Associated Regulator Of MAPK1 Subtype 1), which we’ll get into on part II of this series.


“The kingdom of God is like a man who casts seed upon the soil; and he goes to bed at night and gets up by day, and the seed sprouts and grows—how, he himself does not know. The soil produces crops by itself; first the blade, then the head, then the mature grain in the head”.

Leviticus 2:13 reads: "And every offering of your grain offering you shall season with salt; you shall not allow the salt of the covenant of your God to be lacking from your grain offering. With all your offerings you shall offer salt."

You are salt of the earth. But if salt loses its taste, with what can it be seasoned? It is no longer good for anything but to be thrown out and trampled.”

You are the light of the world…Just so, your light must shine before others, that they may see your good deeds and glorify your heavenly Father.”

Hmm…The River/Tree of Life/Salt/Grain?!

The STYX gene is essential for normal sperm production.

Sperm do what? Swim. How?


Cilia act as cellular antennae to sense environmental cues.

From early embryonic development through adulthood, cilia play crucial roles in unicellular to multicellular organisms.

In fact, once sperm leaves the testis, it’s the cilia that propel it.

During development, cilia of choroid plexus begin as immotile primary cilia, and then transition through multiple primary cilia before undergoing motile multiciliogenesis after birth which is essential for cerebral spinal fluid (CSF) flow.

In other words, cilia are needed to transport/propel cerebral spinal fluid.

Cerebral spinal fluid is directly related to what we will discuss later on called “The Churning of the Ocean’s Milk”.

This has to do with Colostrum and how it’s transported into the cerebral spinal fluid.

The River & the Archipelago

STYX helps regulate a gene called FBXW7.

FBXW7 is also called Archipelago Homolog.

An archipelago is an area that contains a chain or group of islands scattered in lakes, rivers, or the ocean.

The ‘alias’ for FBXW7 is AGO.

AGO means a passage of time, to go forth, or to pass away.

Go forth and SWIM (cilia) through the RIVER!

In mythology, certain coins are put on dead mens' eyes or in their mouths for the journey over the River Styx.

This somehow leads me to believe that in order to pass through the portal between Earth and Hades, or the afterlife, one must navigate through the Archipelago.

Archipelago means "Chief Sea".

The Isle of Man is considered part of an Archipelago.

The Isle of Man is also related to Clathrin, or the Archemedian Spiral, otherwise known as the Golden Spiral of Life.

Major implications both in the physical and spiritual realms!

These references all point to portals found on earth near waterways.

It has been said that when we die our spirit seeks out the nearest body of water and stays there for 3 days until it ascends into the "next life".

The "Archipelago" gene, FBXW7, interacts and regulates the activity of PPARGC1A, also known as human accelerated region 20 (HAR20), or PGC-1α.

PGC-1α is the master regulator of mitochondrial biogenesis.

PGC-1α is a transcriptional coactivator that regulates the genes involved in energy metabolism.

It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis.

Massage therapy stimulates PGC-1α.

And…guess what else might?

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The River Acheron

In Greek mythology, Charon or Kharon is the ferryman of Hades who carries souls of the newly deceased who had received the rites of burial, across the river Acheron (or in some later accounts, across the river Styx).

Yes, we also have a gene called Acheron (LARP6/Death-Associated LA Motif Protein).

It regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2, and is involved with brittle bone disease.

Acheron interacts with VIM/Vimentin.

VIM means “force, power, strength; (New Latin) energy, force”.

Go forth through the RIVER with ENERGY/FORCE/POWER through The Golden SPIRAL!

Vimentin (Epididymis Secretory Sperm Binding Protein) is an filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton.

Microtubules have been said to house the quantum vibration of consciousness.

Go forth through the RIVER with ENERGY/FORCE/POWER through The Golden SPIRAL!?!

VIM/Vimentin is responsible for maintaining cell shape and integrity of the cytoplasm and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis/neurogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. It’s also involved with the stabilization of type I collagen and Apoptosis (cell death).

Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface.

Acheron (LARP6) gene also communicates with a gene called FACT (SUPT16H) which is a chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication, and DNA repair associated with p53/TP53 (Guardian of the Genome) via its association with CK2 (casein kinase II).

Among its related pathways are HIV Transcription Elongation and HIV Life Cycle.

FACT: Water is essential for LIFE FORCE!

FBXW7 is involved in bone homeostasis and negative regulation of osteoclast differentiation (stem cells). Regulates the amplitude of the cyclic expression of hepatic core clock genes and genes involved in lipid and glucose metabolism via ubiquitination and proteasomal degradation. In the DNA Damage Response it facilitates double-strand break repair following phosphorylation by ATM.

FBXW7/STYX help regulate what’s called the SKP1/CUL1/F‐box (SCF) complex involved with NRF1 &NRF2 Activation and turnover.

Hmm…water/life force/quantum consciousness/stem cells/DNA repair/clock/time?!

This is just dissecting one section of Revelation 22:2 and one gene (STYX) in relation to The RIVER.

Is it possible that this RIVER in REV 22:2 is also referenced in other places?

The Churning of the Ocean

The churning of the ocean of milk is a momentous event in Hindu mythology that appears in the Bhagwat Purana, Vishnu Purana, and the Mahabharata. It is the story of the Devas (the Gods) obtaining the ultimate prize of immortality by consuming Amrit, the elixir of immortality.

Churning of the Cosmic Ocean

To churn the primordial ocean, Mount Mandara was used as a churning rod and the snake-king, Vasuki as the churning rope. The Asuras held the head of the snake and the Devas held its tail and they pulled his body alternately, causing the mountain to rotate and the ocean to churn.

Remember I mentioned this “churning of the milk of the ocean earlier?

Colostrum and Cerebral spinal fluid.

They mention the “Head” and the “Tail” eh? Pushing and pulling?

Microtubules and Actin!

Push-me-pull-you: how microtubules organize the cell interior

Microtubule-actin push–pull mechanism

Besides pushing or pulling on the cell cortex, nucleus, spindle, chromosomes, and various membrane-bound organelles, microtubules exert forces on other cytoskeleton systems such as the actin network.

Spindle Positioning: Actin Mediates Pushing and Pulling

To divide asymmetrically, the mitotic spindle is moved from the cell center to the cortex, a process that requires astral microtubules and the microtubule-based motor dynein. New work examining spindle positioning in large oocytes shows that in these cells actin and actin polymerization plays a key role.

“Astral” microtubules?!

Astral means: Relating to or resembling the stars; A supernatural being from the astral plane.

The NUMA1 Gene is the #1 gene for astral microtubules. It’s a Microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.

NUMA means body hair, fur.

This is a reference to CILIA.

Cilia are microtubule-based hair-like organelles that extend from the surface of almost all cell types of the human body and act as cellular antennas. Again, cilia act as cellular antennae to sense environmental cues.

Like sensing the forces of nature perhaps?

And…if you guessed that microtubules and actin are involved in stem cells then you are correct.

The crosstalk between microtubules, actin, and membranes shapes cell division.

Microtubule stabilization enhances the chondrogenesis of synovial mesenchymal stem cells.

Stem cells have also been called the elixir of life!

Induced pluripotent stem cells (iPSCs) launched the golden era of regenerative medicine because of their capacity to generate any cell type within the body.

Consequently, as I’ve written in the past, all these genes and pathways convert back to RHOA/ROCK signaling.

ROCK signaling sits in the middle of microtubule and actin dynamics.

“Upon this ROCK I will build my church”.

As of 2 July 2013, "Styx" officially became the name of one of Pluto's moons. The other moons of Pluto (Charon, Nix, Hydra, and Kerberos) also have names from Greco-Roman mythology related to the underworld.

Hades was the eldest son of Cronus, or Kronos (Father time), the leader and youngest of the first generation of Titans, the divine descendants of Uranus, the sky, and Gaia, the earth.

The period in which Cronus ruled was called the Golden Age, as the people of the time had no need for laws or rules; everyone did the right thing, and immorality was absent.

Imagine that eh?

Hades was often portrayed with his three-headed guard dog Cerberus, the "hound of Hades".

Yes, we have a gene called Cerberus-Related Protein!

Cerberus-Related Protein can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.


The primitive streak is a transient structure whose formation, on day 15 of human development, marks the start of gastrulation, the process in which the inner cell mass in converted into the trilaminar embryonic disc, which is comprised of the three germ layers (ectoderm, mesoderm and endoderm).

In the constellation Cerberus introduced by Johannes Hevelius in 1687, Cerberus is drawn as a three-headed snake, held in Hercules' hand (previously these stars had been depicted as a branch of the tree on which grew the Apples of the Hesperides.)

Hesperides are the nymphs of evening and golden light of sunsets, who were the "Daughters of the Evening" or "Nymphs of the West".

These daughters of Night, guarded the golden apples beyond the Ocean.

Hmm...apples/eternal life/rivers/night?!

Eden Restored...Revelation 22

"Then the angel showed me the river of the water of life, as clear as crystal, flowing from the throne of God and of the Lamb down the middle of the great street of the city. On each side of the river stood the tree of life, bearing twelve crops of fruit, yielding its fruit every month. And the leaves of the tree are for the healing of the nations. No longer will there be any curse. The throne of God and of the Lamb will be in the city, and his servants will serve him. They will see his face, and his name will be on their foreheads. There will be no more night. They will not need the light of a lamp or the light of the sun, for the Lord God will give them light. And they will reign forever and ever."

In summary, THE RIVER (STYX gene) is involved with the very forces of nature. Life, Death, Regeneration!

In part II I will dissect The Tree of Life/Protein ASH.


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