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Ether-A-Go-Go, Bioelectricity, Frequency, & The Fractal Gene


In a recent study, scientists have shown that electric fields can herd cells like flocks of sheep precisely directing the cells' movements by manipulating electric fields. A phenomenon known as electrotaxis.

Electrotaxis, also known as galvanotaxis, is the directed motion of biological cells or organisms guided by an electric field or current.


Our cells can directionally respond to applied electric fields (EFs). A wide variety of biological cells can naturally sense and follow DC electric fields. Such electric fields arise naturally in biological tissues during development and healing.


Bioelectricity


In biology, developmental bioelectricity refers to the regulation of cell, tissue, and organ-level patterning and behavior as the result of endogenous electrically-mediated signaling.

Cells and tissues of all types use ion fluxes to communicate electrically.


Electric currents and fields, ion fluxes, and differences in resting potential across tissues comprise an ancient and highly conserved communicating and signaling system.


Discrete coherent frequencies of electromagnetic waves are able to stabilize cells, whereas others cause a clear destabilization.


A driven set of oscillators condenses in a broad energy range, may activate a vibrational mode in living organisms.


In addition, electromagnetic fields may also influence neural systems in general and human (self) consciousness in particular.


It is further known that the architectural geometry of living cells, like genetic and epigenetic expression, can be disturbed by decoherent wave modalities.


Interestingly, decoherent wave information can also be restored in a reversed process.


12 coherent frequencies:


256, 269.8, 288, 303.1, 324, 341.2, 364.7, 384, 404.5, 432, 455.1, 486 Hz


12 decoherent frequencies:


249.4, 262.8, 278.8, 295.5, 313.4, 332.5, 352.8, 374.3, 394.1, 418.0, 443.2, 470.3 Hz

https://html.scirp.org/file/2-8902709x3.png


The inside/outside discontinuity at the cell surface enabled by a lipid bilayer membrane (capacitor) is at the core of bioelectricity. The plasma membrane was an indispensable structure for the origin and evolution of life itself.


It provided compartmentalization permitting the setting of a differential voltage/potential gradient (battery or voltage source) across the membrane, probably allowing early and rudimentary bioenergetics that fueled cell mechanisms.


Ether-A-Go-Go 1


Voltage-gated potassium (Kv) electric channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.


Ether-A-Go-Go 1 mediates Delayed Rectifier Potassium Currents in myoblasts.


Myoblasts are the embryonic precursors of myocytes (also called muscle cells). Myoblasts differentiate into muscle cells through a process called myogenesis.


Mitogen-Activated Protein Kinase 12 regulates myogenesis. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress.


Again, the mitogen-activated protein kinase family is a major mechanism for the transduction of extracellular signals.


MAPK12 is involved in the regulation of SLC2A1 (GLUT1) expression and basal glucose and negatively regulates SLC2A4 expression.


In the brain, the GLUT1 protein is involved in moving glucose, which is the brain's main energy source, across the blood-brain barrier. The blood-brain barrier acts as a boundary between tiny blood vessels (capillaries) and the surrounding brain tissue; it protects the brain's delicate nerve tissue by preventing many other types of molecules from entering the brain. The GLUT1 protein also moves glucose between cells in the brain called glia, which protects and maintain nerve cells (neurons).


Again, electrotaxis, also known as galvanotaxis, is the directed motion of biological cells or organisms guided by an electric field or current.


Involved with electrotaxis is a gene called KCNH1 Gene, otherwise known as Ether-A-Go-Go 1.


So what is ether?


Ether is defined as:


· “the caelum aetherum of ancient cosmology in which the planets orbit; a shining, fluid substance described as a form of air or fire; air”


· “highest and purest part of the atmosphere; medium supposedly filling the upper regions of space”


· “highest and purest part of the atmosphere; air; heavens, sky; light of day; ethereal matter surrounding a deity”


· “purer upper air of the atmosphere; heaven, sky; theoretical medium supposed to fill unoccupied space and transmit heat and light”


· “to burn, ignite; to blaze, shine”


Noun


· The substance formerly supposed to fill the upper regions of the atmosphere above the clouds, in particular as a medium breathed by deities.


· The medium breathed by human beings; the air.


· The sky, the heavens; the void, nothingness.


· Often as aether and more fully as luminiferous aether: a substance once thought to fill all unoccupied space that allowed electromagnetic waves to pass through it and interact with matter, without exerting any resistance to matter or energy; its existence was disproved by the 1887 Michelson–Morley experiment and the theory of relativity propounded by Albert Einstein (1879–1955).


· The atmosphere or space as a medium for broadcasting radio and television signals; also, a notional space through which Internet and other digital communications take place; cyberspace.


· A particular quality created by or surrounding an object, person, or place; an atmosphere, an aura.


· Diethyl ether (C4H10O), an organic compound with a sweet odour used in the past as an anaesthetic.


· Any of a class of organic compounds containing an oxygen atom bonded to two hydrocarbon groups.


Frequency Gene


Ether-A-Go-Go 1 is connected to an interactive DNA string network involving Na(+)/H(+) Exchanger 3, Calneuron-1, and Calneuron-2, and Neuronal calcium sensor-1 (FREQ gene).


Frequenin/FREQ gene regulates synaptic transmission, helps control the dynamics of nerve terminal growth, is critical for some forms of learning and memory in C. elegans and mammals, regulates corticohippocampal plasticity; and enhancing levels of NCS-1 in the mouse dentate gyrus increases spontaneous exploration of safe environments, potentially linking NCS-1 to curiosity.


The expression of NCS-1 increases in bipolar disorder and some forms of schizophrenia and decreases in inflammatory bowel disease. NCS-1 has also been linked with Autism.


In addition, NCS-1 is significant in intelligence in creating curiosity by its function on dopamine D2 receptors in the dentate gyrus, increasing memory for complex tasks. http://www.physorg.com/news172174436.htm


It would seem that the malfunctioning of these genes and pathways would drive a person into a state of fear and would incline an individual to stay home due to a lack of curiosity.


FREQ is associated with frequency-dependent increases in neurotransmission. Of which calcium ion binding and magnesium ion binding are important factors.


FREQ gene interacts with a gene called PICK.


PICK plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors.


PICK is important because it activates a gene called ASIC1 otherwise known as Brain Sodium Channel 2.


The ASIC1/Brain Sodium Channel 2 functions in learning, pain transduction, touch sensation, and development of memory and fear.


It mediates glutamate-independent Ca(2+) entry into neurons upon acidosis and this Ca(2+) overloading is toxic for cortical neurons.


ASIC1/Brain Sodium Channel 2 modulates activity in the circuits underlying innate fear.


It’s inhibited by anti-inflammatory compounds like salicylic acid, otherwise known as white willow.


Now, this is vital to understand...


Once these channels are not at optimal functioning capacity it impacts your Ribosomal machinery.


Ribosomes are macromolecular machines, found within all living cells, which perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to form polypeptide chains.


The Breakdown


So basically a malfunction of the FREQ (frequency) gene causes a domino effect that impacts PICK, which then impacts ASIC1, which then, in turn, impacts Ribosomal Protein L19, which then leaves us wide open for viral infection.


The Ribosomal Protein L19 related pathways are Viral mRNA Translation and Influenza Viral RNA Transcription and Replication.


Back to PICK…


PICK, Protein Interacting with PRKCA 1, communicates with SLC6A2 Gene otherwise known as NET.


Malfunctions in NET cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation, and syncope.


Among its related pathways are Sympathetic Nerve Pathway (Neuroeffector Junction) and Synaptic vesicle cycle.


Neuropeptide Y regulates the Sympathetic Nerve Pathway (Neuroeffector Junction).

Neuropeptide Y is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.


Diseases associated with NPY include Eating Disorder and Adjustment Disorder, a disease of mental health that is an abnormal and excessive emotional and behavioral reaction to life stress.


Some emotional signs of adjustment disorder are sadness, hopelessness, lack of enjoyment, crying spells, nervousness, anxiety, desperation, feeling overwhelmed, and thoughts of suicide, performing poorly in school/work, etc.


Stay home in fear, eat garbage, and learn nothing new would generally be what transpires when the aforementioned are out of balance.


Neuropeptide Y is regulated by Fractalkine (CX3CL1).


The Fractal Gene


Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells.


It has also been found to be essential for microglial cell migration.


CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.


Fractalkine is thought to contribute to inflammatory brain disorders. Fractalkine is up-regulated and released in the brain tissue and cerebrospinal fluid of those with HIV-1 associated dementia Cotter et al (2002).


The release of FKN from apoptotic cells appears to guide the immune response to minimize further tissue damage and preserve tissue function.


So as you can see it is VITAL to balance Fractalkine in order to assist in minimizing tissue damage and regulating inflammatory brain disorders.


Overactive microglia is one of the main causes of neuronal damage and death.


The deficiency of CX3CR1 is associated with microglial activation.


Fractalkine also acts as a coreceptor for HIV-1.


Fractalkine/CX3CL1: A Potential New Target for Inflammatory Diseases (R)


Fractalkine plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.


One disease associated with CX3CL1 is Vasculitis.


Vasculitis is an inflammation of the blood vessels. It happens when the body's immune system attacks the blood vessel by mistake. It can happen because of an infection, a medicine, or another disease. The cause is often unknown. Vasculitis can affect arteries, veins, and capillaries. Arteries are vessels that carry blood from the heart to the body's organs. Veins are the vessels that carry blood back to the heart. Capillaries are tiny blood vessels that connect the small arteries and veins. When a blood vessel becomes inflamed, it can narrow, making it more difficult for blood to get through Close off completely so that blood can't get through Stretch and weaken so much that it bulges. The bulge is called an aneurysm. If it bursts, it can cause dangerous bleeding inside the body. Symptoms of vasculitis can vary, but usually include fever, swelling, and a general sense of feeling ill. The main goal of treatment is to stop the inflammation.


Life is ultimately an electrochemical enterprise as we are essentially a hydro-electric machine at our core.


Frequency determines physiology.


“Control the geometry; control the biology” – Joey Phillips





Joey Phillips is a Husband, Father, Medical Researcher, Epigeneticist Health Advocate, CEO of ReverseFX, and CEO of DNA Diligence. Since 2015, He's been providing professional consulting services to clients from around the globe. 

Joey has devoted over 20,000 research hours in the health arena.

Understanding the current medical field is flawed and failing, Joey decided not to pursue a medical degree. Rather, he is self-educated through an unwavering curiosity about how things work in the body.

"Don't confuse education with schooling" - Elon Musk

Having studied law, the etymology of language, history, and religion, Joey realized that all his efforts to acquire more freedom didn't mean a thing without good health. Having good health is the first key to obtaining independence from a broken system. In an effort to reduce costs associated with unnecessary testing DNA Diligence™ was born. Being constantly on the hunt for the latest in cutting-edge research gives Joey Phillips a unique advantage in the health industry. 

"If you don't know what you're looking for, you'll never know where to find it." "In a sea of possibilities, pattern recognition is the key to unlocking the door to new therapeutic interventions." - Joey Phillips


https://www.dna-diligence.com/bookings-checkout/health-consultation/book



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Sources:

https://phys.org/news/2020-06-electric-fields-herd-cells-flocks.html?fbclid=IwAR3LUsBKcg8mKscR9cDM8rgAF2asA6DvpOkkc1xA4Gz_zbRfG3xn33eLy5g

https://en.wikipedia.org/wiki/Electrotaxis#:~:text=Electrotaxis%2C%20also%20known%20as%20galvanotaxis,tissues%20during%20development%20and%20healing.

https://experiments.springernature.com/articles/10.1007/978-1-4939-7701-7_23

https://www.semanticscholar.org/paper/Influence-of-electrotaxis-on-cell-behaviour.-Cortese-Palam%C3%A0/c95614c6fce803417c3dbf1f8a07877394965008

https://slideplayer.com/slide/13397844/

https://en.wiktionary.org/wiki/ether

https://en.wikipedia.org/wiki/Bioelectricity

https://neuroquantology.com/article.php?id=1450

https://www.scirp.org/journal/paperinformation.aspx?paperid=82944#ref13

https://www.genecards.org/Search/Keyword?queryString=Electrotaxis

https://ghr.nlm.nih.gov/gene/MAPK12

https://ghr.nlm.nih.gov/gene/SLC2A1

https://en.wikipedia.org/wiki/Neuronal_calcium_sensor-1

https://www.genecards.org/cgi-bin/carddisp.pl?gene=PICK1&keywords=PICK1

https://www.genecards.org/cgi-bin/carddisp.pl?gene=ASIC1

https://en.wikipedia.org/wiki/Ribosome

https://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC6A2

https://www.genecards.org/cgi-bin/carddisp.pl?gene=NPY

https://en.wikipedia.org/wiki/Adjustment_disorder

https://en.wikipedia.org/wiki/CX3CL1

https://www.sciencedirect.com/topics/neuroscience/fractalkine

https://www.genecards.org/cgi-bin/carddisp.pl?gene=CX3CL1

https://www.malacards.org/card/vasculitis

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