Recent research indicates that the gene CD147, otherwise known as Emprin, is a Target for COVID-19 Treatment.
CD147, a receptor on host cells, also known as Basigin and Emprin, is a novel route for the SARS-CoV-2 invasion. Thus, compounds that interfere in the spike protein/CD147 interaction or CD147 expression may inhibit viral invasion and dissemination among other cells, including in progenitor/stem cells.
CD147 is a highly glycosylated transmembrane protein of the immunoglobulin superfamily that acts as the main upstream stimulator of matrix metalloproteinases (MMPs).
In another study, we see that “SARS-CoV-2 invades host cells via a novel route: CD147-spike protein.”
And again another study states “BREAKING! New Coronavirus Research Shows That The SARS-CoV-2 Coronavirus Has A Fourth Route Of Attacking Human Host Cells Making It A Real Super Virus.”
Let’s break down this EMPRIN (CD147 gene) and do our due DNA Diligence!
First, the BSG Gene has aliases of:
· Ok Blood Group
First, EMPRIN is also known as Aspirin.
Aspirin is used to reduce fever and relieve mild to moderate pain from conditions such as muscle aches, toothaches, common cold, and headaches. It may also be used to reduce pain and swelling in conditions such as arthritis. Aspirin is known as a salicylate and a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking a certain natural substance in your body to reduce pain and swelling.
Protective Effect of Aspirin on COVID-19 Patients
“COVID-19 has a high infection rate and mortality, and serious complications such as heart injury cannot be ignored. Cardiac dysfunction occurred in COVID-19 patients, but the law and mechanism of cardiac dysfunction remain unclear. The occurrence of progressive inflammatory factor storm and coagulation dysfunction in severe and fatal cases of NCP points out a new direction for reducing the incidence of severe and critically ill patients, shortening the length of duration in severe and critically ill patients and reducing the incidence of complications of cardiovascular diseases.
Aspirin has the triple effects of inhibiting virus replication, anticoagulant, and anti-inflammatory, but it has not received attention in the treatment and prevention of NCP. Although Aspirin is not commonly used in the guidelines for the treatment of NCP, it was widely used in the treatment and prevention of a variety of human diseases after its first synthesis in 1898. Subsequently, aspirin has been confirmed to have an antiviral effect on multiple levels. Moreover, one study has confirmed that aspirin can inhibit virus replication by inhibiting prostaglandin E2 (PGE2) in macrophages and upregulation of type I interferon production. Subsequently, pharmacological studies have found that aspirin as an anti-inflammatory and analgesic drug by inhibiting cox-oxidase (COX). Under certain conditions, the platelet is the main contributor of the innate immune response, studies have found that in the lung injury model in dynamic neutrophil and platelet aggregation.
In summary, the early use of aspirin in COVID-19 patients, which has the effects of inhibiting virus replication, anti-platelet aggregation, anti-inflammatory, and anti-lung injury, is expected to reduce the incidence of severe and critical patients, shorten the length of hospital duration and reduce the incidence of cardiovascular complications.”
Is it safe to take aspirin to treat coronavirus symptoms?
For adults, it’s safe to take aspirin for pain or fever from COVID-19. Due to initial concern that anti-inflammatory drugs like and may worsen coronavirus symptoms, the World Health Organization initially recommended against the use of these anti-inflammatory drugs. However, they reversed that recommendation several days later and no longer recommend against ibuprofen or other anti-inflammatory drugs, including aspirin. Children and teenagers should not take aspirin due to the risk of it causing a life-threatening condition called Reye’s syndrome.
Willow Bark (Salix alba)
Willow bark has been used for centuries as a treatment for pain, headache, and inflammatory conditions such as bursitis and tendinitis. The bark of white willow contains salicin, the chemical that was used to develop aspirin.
For centuries, herbal medicines have been